From AHA 2025 in New Orleans, Dr. Clyde Yancy from Northwestern University delivers an important update on breakthrough therapies transforming the management of resistant hypertension and highlights two revolutionary drug classes—aldosterone synthase inhibitors and endothelin receptor antagonists. With the advent of these newer classes, a new era of precision medicine in blood pressure control is on the horizon. This paradigm shift extends beyond achieving the <130/80 mmHg target to protecting the entire CKM (cardiovascular-kidney-metabolic) spectrum, including prevention of stroke, heart disease, chronic kidney disease, and cognitive decline.
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Clinical Perspective on New Therapies in Resistant Hypertension
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Overview
From AHA 2025 in New Orleans, Dr. Clyde Yancy from Northwestern University delivers an important update on breakthrough therapies transforming the management of resistant hypertension and highlights two revolutionary drug classes—aldosterone synthase inhibitors and endothelin receptor antagonists. With the advent of these newer classes, a new era of precision medicine in blood pressure control is on the horizon. This paradigm shift extends beyond achieving the <130/80 mmHg target to protecting the entire CKM (cardiovascular-kidney-metabolic) spectrum, including prevention of stroke, heart disease, chronic kidney disease, and cognitive decline.
Provider(s)/Educational Partner(s)
- video
The Lp(a)-Lowering Landscape: Navigating Current and Future Therapeutic Options
Show more - video
DARE AF Trial: Dapagliflozin to Reduce AF Burden After Catheter Ablation in Patients Without Diabetes or Heart Failure
Show more - video
DECAF Trial: Does Eliminating Coffee Reduce Atrial Fibrillation Recurrence in Symptomatic Patients?
Show more - video
POLY HF Trial: A Polypill Strategy for Heart Failure With Reduced Ejection Fraction (HFrEF)
Show more - video
Precision Medicine in Obstructive HCM Care: The Promise of Cardiac Myosin Inhibitors
Show more - video
The LDL-C-Lowering Landscape: Navigating Current and Future Therapeutic Options
Show more - video
ADAPT AF-DES: Antithrombotic Strategies Beyond 12 Months for Patients With AF Treated With Drug-Eluting-Stents
Show more - video
OCEAN Trial at AHA 2025: Anticoagulation After AF Ablation in High-Risk Patients
Show more - video
Highlights of the Latest Hypertension Guidelines
Show more
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